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Dr. Umar Aitsaam

About

Clinical Pharmacist and Master’s student in Clinical Pharmacy with research interests in pharmacovigilance, behavioral interventions in mental health, and AI applications in clinical decision support. Experience includes digital health research with Bloomsbury Health (London) and pharmacovigilance practice in patient support programs. Published work covers drug awareness among healthcare providers, postpartum depression management, and patient safety reporting.

Recent Posts

2025-10-27 10:38:36

Mechanisms of Heavy Metal–Induced Hypoxia

Heavy metals such as lead, cadmium, arsenic, and mercury disrupt oxygen homeostasis by impairing mitochondrial respiration, stabilizing HIF-1α, generating oxidative stress, and inhibiting hemoglobin synthesis, leading to cellular and systemic hypoxia across multiple organ systems.

2025-10-24 03:30:18

Arsenic Exposure Biomarkers for HTMC Compliance

Arsenic exposure biomarkers link drinking-water contamination to vascular injury, insulin resistance via muscle atrophy, and Th2-dominant airway disease, informing HTMC standards.

2025-10-24 03:17:02

Effects of Cr, Mn, and Se on RBCs: HTMC Certification Insights

HTMC heavy metal certification can leverage NHANES-based evidence linking chromium to poorer erythrocyte indices, manganese elevation to microcytic features, and selenium to modest protection, informing limits, flags, and supplier controls.

2025-10-24 02:55:38

Mercury Hematological Effects: Guidance for HMTC

A systematic review links mercury exposure to diverse mercury hematological effects, including anemia and leukocyte changes, with severe cases and deaths, informing HTMC testing and thresholds.

2025-10-23 14:44:57

Cadmium-Induced Anemia Mechanisms for HTMC Certification

This study reveals cadmium induces a complex anemia via hemolysis, renal EPO suppression, and systemic iron dysregulation, leading to “apparent iron deficiency.” Certification programs must look beyond simple iron status and consider renal function and inflammatory markers for accurate risk assessment.

2025-10-23 14:06:03

Heavy Metal Interference in Heme Biosynthesis

Heavy Metal Tested and Certified porphyria standards should hinge on ALAD and ferrochelatase inhibition, iron-regulated steps, and matrix-specific diagnostic thresholds derived from this review.

2025-10-23 13:29:12

Heavy Metal Exposure and Mitochondrial Dysfunction Review

This review elucidates how heavy metal exposure induces mitochondrial dysfunction driving neurodegenerative diseases, highlighting critical molecular mechanisms, disease-specific effects, and implications for regulatory certification and neurotoxicology research.