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An average adult in the United States eats about 7–9 mg of aluminum per day in their food. Even though the human body has no biological need for this metal. Aluminum is so omnipresent that trace amounts are found in almost everyone, yet it can accumulate over time, which is why even “low” exposures are worth reducing.

Aluminum (Al)

Researched by:

  • Divine Aleru ID
    Divine Aleru

    User avatarDivine Aleru is an accomplished biochemist and researcher with a specialized background in environmental toxicology, focusing on the impacts of heavy metals on human health. With deep-rooted expertise in microbiome signatures analysis, Divine seamlessly blends rigorous scientific training with her passion for deciphering the intricate relationships between environmental exposures and the human microbiome. Her career is distinguished by a commitment to advancing integrative health interventions, leveraging cutting-edge microbiome research to illuminate how toxic metals shape biological systems. Driven by curiosity and innovation, Divine is dedicated to translating complex environmental findings into actionable insights that improve individual and public health outcomes.

    Read More

October 24, 2025

Aluminum is a pervasive metal found in a wide range of consumer products, from food packaging and cookware to medications and personal care items. Although often overlooked, aluminum exposure can accumulate over time, posing long-term health risks, especially to vulnerable populations like infants, children, and individuals with kidney conditions.

Researched by:

  • Divine Aleru ID
    Divine Aleru

    User avatarDivine Aleru is an accomplished biochemist and researcher with a specialized background in environmental toxicology, focusing on the impacts of heavy metals on human health. With deep-rooted expertise in microbiome signatures analysis, Divine seamlessly blends rigorous scientific training with her passion for deciphering the intricate relationships between environmental exposures and the human microbiome. Her career is distinguished by a commitment to advancing integrative health interventions, leveraging cutting-edge microbiome research to illuminate how toxic metals shape biological systems. Driven by curiosity and innovation, Divine is dedicated to translating complex environmental findings into actionable insights that improve individual and public health outcomes.

    Read More

Last Updated: 2025-10-20

Our team of researchers are constantly monitoring and summarizing the latest research,
and we continue to update our pages to ensure you have the most accurate information.

Note on the last update: One new meta analysis added

Divine Aleru

Divine Aleru is an accomplished biochemist and researcher with a specialized background in environmental toxicology, focusing on the impacts of heavy metals on human health. With deep-rooted expertise in microbiome signatures analysis, Divine seamlessly blends rigorous scientific training with her passion for deciphering the intricate relationships between environmental exposures and the human microbiome. Her career is distinguished by a commitment to advancing integrative health interventions, leveraging cutting-edge microbiome research to illuminate how toxic metals shape biological systems. Driven by curiosity and innovation, Divine is dedicated to translating complex environmental findings into actionable insights that improve individual and public health outcomes.

Aluminum is a ubiquitous metal that people encounter daily through food, water, and consumer products. It ranks among the top metals of concern in public health due to its widespread use and potential toxicity. Aluminum has no known biological function in the human body, yet it can accumulate in tissues over time.[1] Prolonged exposure has been linked to neurological and bone disorders, especially in vulnerable populations like infants and kidney patients.[2] For these reasons, the Heavy Metal Tested & Certified (HMTC) program includes aluminum in its “Top 8” metals to monitor and minimize. Proactively controlling aluminum exposure is essential to safeguard infants, children, and consumers and to stay ahead of emerging regulatory scrutiny.

Overview

Aluminum (Al) is a silvery-white, lightweight metal and the most abundant metal in Earth’s crust (8%).[3] It is not found in pure form in nature due to its reactivity, existing instead as Al³⁺ compounds like aluminum oxides, hydroxides, and sulfates in soil, rocks, and clays.[4] Industrially, refining bauxite ore produces metallic aluminum, which is used in products such as beverage cans, foil, and cookware. Aluminum compounds, including alum (aluminum sulfate), are used in water treatment and as food additives and pharmaceuticals.[5] Only a small fraction of ingested aluminum is absorbed into the bloodstream, and healthy kidneys excrete most of it.[6] However, problems arise with high or prolonged exposure, or when excretion is impaired. Aluminum’s Al³⁺ ions bind strongly to biological molecules, disrupting cellular functions.[7] This can lead to accumulation in tissues like bone and generate oxidative stress, damaging proteins and DNA, which is linked to neurological damage and other toxic effects.[8][9]

Major Sources of Exposure

The omnipresence of aluminum means everyone has some exposure. But because of its potential to accumulate and interfere with cellular processes, chronic exposure is a public health concern, especially for populations that are more susceptible to its effects.[10] Exposure sources are categorized into three main pathways: dietary, environmental, and occupational. For most people, diet is the main aluminum source, whereas industrial workers receive much higher exposures than the general population.

Exposure PathwayExamples and Routes
Dietary An average adult in the United States consumes about 7–9 mg of aluminum per day from food and beverages.[11] Some foods are notable contributors. For example, grain products may contain aluminum from leavening agents, and tea leaves naturally accumulate aluminum from soil.[12] Vegetables also take up more aluminum.[13] Even infant formula has been found to contain aluminum in some cases (from ingredients and packaging), making it a source of early-life exposure.[14]
Environmental Drinking water generally contributes only a minor portion of aluminum intake (usually <5%). Aluminum may be present in tap water if aluminum sulfate was used in treatment, but water utilities aim to keep residual levels low.[15] A recent study showed that cooking meals wrapped in aluminum foil can measurably raise the aluminum levels in the food and subsequently in the person’s body.[16] Medications and personal care products like antacids and antiperspirant deodorants can also be significant hidden sources of exposure.
OccupationalWorkers in aluminum smelting plants, foundries, or fabrication facilities may inhale aluminum oxide dust or fumes.[17] Welders using aluminum can inhale fine particulate. Over months and years, this inhaled aluminum can deposit in the lungs and enter circulation.[18] Occupational studies have noted that aluminum dust exposure is linked to lung changes and reduced lung function in long-term workers.[19] Industrial exposures can also elevate blood and urine aluminum well above normal, which in some cases has led to cognitive effects.

Adverse Health Effects

Aluminum’s health effects have been studied in both toxicological research and human epidemiological studies. Evidence indicates that chronic aluminum exposure can harm multiple organ systems, with the nervous system and skeletal system being primary targets.[20] The weight of evidence shows that aluminum is not harmless. It is a bio-accumulative toxicant with effects documented in both clinical settings and population studies. The diverse health impacts, from learning deficits in children to potential contributions to neurodegenerative disease and bone frailty, highlight the importance of controlling contamination in foods, supplements, and consumer products.[21]

Health EffectEvidence and Mechanisms
Neurological EffectsAluminum is a neurotoxin at high concentrations. Long-term dialysis patients with aluminum-contaminated fluids developed encephalopathy from aluminum accumulating in the brain.[22] In infants, early exposure, especially via intravenous nutrition, has been linked to lower neurodevelopmental scores. Studies show that each day of high aluminum exposure in preterm infants was associated with cognitive score reductions.[23] Studies have also linked aluminum to neurodegenerative diseases like Alzheimer’s, though causality is debated.[24]
Bone and Skeletal EffectsAluminum interferes with bone mineralization, leading to osteomalacia, particularly in cases of chronic aluminum exposure[25]. This was initially noted in dialysis patients where aluminum accumulated in bone tissue and bound phosphate, preventing proper bone mineral formation.[26] High aluminum exposure in children, especially those with kidney disease, can impair bone growth. A review concluded that aluminum exposure from parenteral nutrition in neonates impairs bone mineralization.[27]
Immune System EffectsExcess aluminum has been shown to disrupt immune cell function in laboratory studies, causing inflammation and reduced macrophage activity.[28][29] Aluminum adjuvants in vaccines can cause local inflammatory nodules in some individuals, but widespread immune dysfunction is not typically observed from typical exposures.[30]
Respiratory EffectsInhaled aluminum dust from occupational exposure can cause chronic lung inflammation.[31] Prolonged exposure can lead to aluminosis, a fibrotic lung condition with symptoms like coughing and reduced pulmonary function.[32] Animal studies confirm that aluminum particulates cause lung fibrosis and damage airway cells.[33]
Reproductive and Developmental ToxicityHigh doses of aluminum in animal studies have shown potential harm to the developing nervous system and reproductive organs.[34] Although human data is inconclusive, aluminum can cross the placenta and could affect fetal development.[35] Pregnant women with high aluminum exposure, such as from antacids or environmental sources, may be at risk.
Vulnerable Groups (Infants, Pregnant Women, Renal Patients)Infants and young children are highly vulnerable to aluminum toxicity due to their immature detoxification systems and rapidly developing brains and bones.[36] Formula-fed infants or those needing intravenous feeding are at particular risk for aluminum accumulation. Pregnant women and the fetus may also be impacted due to aluminum crossing the placenta.[37] Patients with kidney impairment (including those on dialysis) cannot clear aluminum efficiently, leading to higher levels and potential damage to the brain and bones.[38]

Consumer Relevance

Aluminum exposure is often hidden in plain sight, with many consumer products containing aluminum without clear labeling or warnings. From food additives like baking powder to personal care items such as deodorants and over-the-counter medications like antacids, aluminum is an ingredient many consumers overlook.[39] This hidden exposure can contribute to a gradual build-up of aluminum in the body, which poses particular risks to sensitive populations such as infants, children, and those with impaired kidney function.[40] Below is a detailed table highlighting the various sources of aluminum found in consumer products and the associated risks, providing a clearer picture of where aluminum may show up in real life.

Product/SourceDescription and Evidence
Infant Formula & Baby FoodSome infant formulas, especially those based on soy, have elevated aluminum content due to ingredients and processing.[41] Babies consuming these formulas may ingest significantly more aluminum than breastfed infants.[42] Parents can check if a brand uses aluminum-containing additives. Where possible, use breastmilk or rotate formula types to diversify sources.
Processed Foods & BakingBaking powder and self-rising flour often contain sodium aluminum phosphate or aluminum sulfate.[43] Processed cheese and cake mixes may use aluminum-based emulsifiers.[44] Frequent consumption of these foods can increase daily aluminum intake.
Cookware & Aluminum FoilUncoated aluminum pots, pans, and foil can leach metal when cooking.[45] To reduce risk, use anodized aluminum cookware, cast iron, stainless steel, or enamel-coated pots. When using foil, avoid contact with acidic ingredients (line with parchment paper or use a different storage wrap for marinating).
Canned Goods & DrinksAluminum canned foods are everywhere. Cans are typically lined to block aluminum, so leaching is minimal.[46] However, if a can is dented or scratched inside, or if acidic foods are stored for very long periods, some aluminum could migrate.[47] Overall, canned foods contribute only trace aluminum in most cases.
Antiperspirants & CosmeticsThe active ingredient in antiperspirant deodorants is usually an aluminum salt.[48] These compounds form temporary plugs in sweat ducts.[49] A small amount of aluminum from each application may penetrate the skin. For most people, this is minor, but those concerned can choose aluminum-free deodorants.
MedicationsAntacids are a major source: e.g., one tablespoon of Maalox may contain 50–100 mg of aluminum.[50] If you rely on daily antacids or buffered aspirin, discuss alternatives with your doctor (such as calcium or magnesium-based antacids).

Regulatory Snapshot

The United States Environmental Protection Agency (EPA) sets the standards for public water systems, including bottled water. The EPA’s recommended SMCL for aluminum in drinking water is 0.05−0.20 mg/L, based on factors like taste, odor, and color.[51] In Europe, the European Food Safety Authority (EFSA) has set a Tolerable Weekly Intake (TWI) of 1 mg/kg body weight, noting that high aluminum intake from food additives may surpass this value in some populations.[52] Despite these regulations, food labels rarely indicate the aluminum content, making it challenging for consumers to make informed decisions. The World Health Organization (WHO) has not set a health-based guideline for aluminum in drinking water. However, recommended practical levels have been established to reduce aluminum concentrations in treated water: 0.1 mg/l or lower for large water treatment plants, and 0.2 mg/l or lower for smaller facilities.[53] Given the potential for chronic exposure, international regulatory agencies need to update their guidelines to create clearer, more universal standards, especially for vulnerable groups like infants and pregnant women.

Implications for the HMTC Program

The HMTC program applies the ALARA (As Low As Reasonably Achievable) principle to aluminum in consumer products, prioritizing the safety of infants and children, who are particularly vulnerable to heavy metal exposure. This approach is critical in a regulatory environment where aluminum limits are either non-existent or inconsistent. By enforcing stricter aluminum limits than those required by regulatory bodies, HMTC ensures that products meet the highest safety standards, offering a transparent solution for consumers concerned about hidden sources of aluminum in their daily lives. HMTC-certified products undergo rigorous testing and meet strict thresholds for aluminum content, often well below the tolerable intake levels set by agencies like the FDA, EFSA, and WHO. This provides consumers with confidence in the safety of their food, cosmetics, and healthcare products. By prioritizing the minimization of aluminum exposure, HMTC certification allows brands to stay ahead of tightening regulations, positioning them as leaders in consumer health.

Research Feed

The impact of aluminum exposure on human health
August 19, 2023

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Aluminum Effects in Infants and Children
December 1, 2019

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Pathophysiological mechanisms of aluminum toxicity
March 4, 2020

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Bauxite mining and alumina refining: process description and occupational health risks

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Chronic Aluminum Intake Causes Alzheimer’s Disease: Applying Sir Austin Bradford Hill’s Causality Criteria
May 19, 2014

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Is aluminum exposure a risk factor for neurological disorders?
June 6, 2018

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Aluminum environmental pollution: the silent killer
July 1, 2021

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Aluminum Vaccine Adjuvants: Are they Safe?
June 1, 2011

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Aluminum Exposure and Heavy Metal Certification: Health Risks and Thresholds

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Exposure to Aluminum in Drinking Water and the Risk of Developing Alzheimer’s Disease: A Bibliometric Analysis and Systematic Evaluation
August 25, 2024

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The aluminium content of infant formulas remains too high
October 8, 2013

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Effect of an aluminum foil-processed diet on internal human aluminum burden
May 29, 2023

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Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts
September 18, 2014

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Accelerated lung function decline in an aluminium manufacturing industry cohort exposed to PM2.5: an application of the parametric g-formula
October 14, 2019

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Preclinical and Epidemiological Mucoskeletal Evidence of Aluminium Toxicity: A Systematic Review
July 23, 2023

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Aluminum-Induced Entropy in Biological Systems: Implications for Neurological Disease
October 2, 2014

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Toxicity and Biokinetics Following Pulmonary Exposure to Aluminum: A Review published in Toxicology
June 30, 2024

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Aluminum reproductive toxicity: a summary and interpretation of scientific reports
September 1, 2020

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The Effect of Aluminum Exposure on Maternal Health and Fetal Growth in Rats
November 22, 2022

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Widespread Heavy Metals in Baby Food Reveal Urgent Regulatory Gaps
What was reviewed? This narrative review critically examined the prevalence of toxic heavy metals in baby food, specifically inorganic arsenic, lead, mercury, and cadmium, in commercially available infant and toddler foods in the United States. It also evaluated the adequacy of existing national food safety policies and regulatory frameworks for mitigating heavy metal exposure in young children. Drawing upon peer-reviewed literature, government reports, and independent investigations, the review aimed to expose regulatory gaps and encourage policy reform in line with current toxicological evidence. Who was reviewed? The review focused on data involving commercial baby food manufacturers in the U.S., including internal documents obtained from seven major companies such as Gerber, Beech-Nut, Earth's Best Organic, and HappyBABY. It also incorporated findings from regulatory bodies (e.g., FDA), non-profits (e.g., Healthy Babies Bright Futures, Clean Label Project), and congressional investigations (notably the U.S. House Subcommittee on Economic and Consumer Policy). Although not limited to specific demographics, the analysis centered on food products consumed by infants and toddlers (ages 0–36 months). Most important findings The review identified widespread and troubling levels of heavy metal contamination—particularly arsenic, lead, and cadmium—in infant and toddler food products, with arsenic especially prevalent in rice-based foods and mercury also detected, albeit less frequently. A critical issue highlighted was the reliance on ingredient-level testing rather than testing of finished products, a practice that significantly underestimates true exposure risks. Regulatory frameworks were found to be inadequate. In the United States, only inorganic arsenic in infant rice cereal is subject to a binding limit (100 ppb), while most other heavy metals remain unregulated in baby food. Internal manufacturer thresholds often exceed even this basic standard. Moreover, existing studies and industry reports tend to focus on the presence of toxicants rather than employing comprehensive risk assessments based on exposure dosage and toxicological thresholds. In response to regulatory gaps, some independent organizations have set their own limits: for example, the Baby Food Safety Act proposes action levels such as 5 ppb lead for general infant foods and 10 ppb for cereals, while Consumer Reports recommends limits as low as 1 ppb for lead in juices. Meanwhile, certification bodies like the Clean Label Project have implemented even stricter voluntary standards for heavy metal content, offering a higher level of consumer protection in the absence of robust federal oversight. Heavy MetalHealth Risks in ChildrenFDA Infant Standard (if any)Notable ExceedancesArsenicNeurotoxicity, IQ reduction100 ppb (rice cereal only)Detected in 100% of rice productsLeadPermanent cognitive damageNone universalFound in 37–88% of samplesMercuryPrenatal neurodevelopmental harmNone specific to baby foodLimited detectionCadmiumReduced IQ, increased ADHD riskNone specific to baby foodFound in 57–100% of grain samples Key implications The absence of authoritative, enforceable heavy metal limits for infant and toddler foods in the U.S. constitutes a significant public health oversight, especially considering the biological vulnerability of this age group. The review calls for urgently adopting binding, risk-based regulatory standards under the ALARA principle. It also emphasizes that risk communication must strike a balance between transparency and parental reassurance to avoid unnecessary dietary restrictions. Until federal standards are established and enforced, third-party certifications like those from the Clean Label Project serve as crucial interim safeguards. Finally, the review underscores the importance of testing finished products—rather than just raw ingredients—to obtain accurate exposure assessments. Citation Bair EC. A Narrative Review of Toxic Heavy Metal Content of Infant and Toddler Foods and Evaluation of United States Policy. Front Nutr. 2022;9:919913. doi:10.3389/fnut.2022.919913
Aluminium migration into beverages: Are dented cans safe?
July 30, 2008

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Corrosion Behavior of Aluminium-Coated Cans
January 24, 2023

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Aluminum Inhibits Erythropoiesis in-vitro: HTMC Guide

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Aluminum Exposure in Lebanese Infant Foods: Health Risk Insights

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Heavy Metal Toxicity Mechanisms: Landmark Review

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Aluminum-Induced Anemia: Heavy Metal Certification Standards

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Aluminum Bioaccessibility in Infant Cereals: Implications for Heavy Metal Certification

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Deodorants and antiperspirants: New trends in their active agents and testing methods
March 21, 2023

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Real-time observation of the interaction between aluminium salts and sweat under microfluidic conditions
March 18, 2021

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Investigation of aluminum content of imported candies and snack foods in Taiwan
June 21, 2016

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Drinking water disparities and aluminum concentrations: Assessing socio-spatial dimensions across an urban landscape
May 2, 2023

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The ALARA Principle

The ALARA principle (“As Low As Reasonably Achievable”) is a safety standard that minimizes harmful exposures like heavy metals beyond regulatory compliance. By applying continuous reduction practices, it ensures food and consumer products meet the lowest feasible contamination levels, protecting vulnerable populations from cumulative risks.

References

  1. Aluminum Effects in Infants and Children. . Mark R. Corkins, COMMITTEE ON NUTRITION, Steven A. Abrams, George J. Fuchs, Praveen S. Goday, Tamara S. Hannon, Jae H. Kim, C. Wesley Lindsey, Ellen S. Rome;. (Pediatrics December 2019; 144 (6): e20193148.)
  2. The impact of aluminum exposure on human health.. Bonfiglio, R., Scimeca, M. & Mauriello, A.. (Arch Toxicol 97, 2997–2998 (2023).)
  3. Human exposure to aluminum.. Epstein SG.. (Environ Geochem Health. 1990 Mar;12(1-2):65-70.)
  4. Bauxite mining and alumina refining: process description and occupational health risks.. Donoghue AM, Frisch N, Olney D.. (J Occup Environ Med. 2014 May;56(5 Suppl):S12-7.)
  5. Chronic Aluminum Intake Causes Alzheimer’s Disease: Applying Sir Austin Bradford Hill’s Causality Criteria.. Walton JR.. (Journal of Alzheimer’s Disease. 2014;40(4):765-838.)
  6. Aluminum Effects in Infants and Children. . Mark R. Corkins, COMMITTEE ON NUTRITION, Steven A. Abrams, George J. Fuchs, Praveen S. Goday, Tamara S. Hannon, Jae H. Kim, C. Wesley Lindsey, Ellen S. Rome;. (Pediatrics December 2019; 144 (6): e20193148.)
  7. The chemistry of aluminum as related to biology and medicine.. Martin RB.. (Clin Chem. 1986 Oct;32(10):1797-806)
  8. Is aluminum exposure a risk factor for neurological disorders?. Inan-Eroglu, E., & Ayaz, A. (2018).. (Journal of Research in Medical Sciences : The Official Journal of Isfahan University of Medical Sciences, 23, 51.)
  9. Pathophysiological mechanisms of aluminum toxicity.. Bojanić, N., Milenković, J., Stojanović, D., Milojković, M., Djindjić, N., & Gmijović, M. (2020).. (Acta Medica Medianae, 59(1), 100-109.)
  10. The health effects of aluminum exposure.. Klotz K, Weistenhöfer W, Neff F, Hartwig A, van Thriel C, Drexler H.. (Dtsch Arztebl Int. 2017;114:653–9)
  11. Public Health Statement for Aluminum. Agency for Toxic Substances and Disease Registry. (CAS#: 7429-90-5)
  12. Aluminum environmental pollution: the silent killer.. Alasfar RH, Isaifan RJ.. (Environ Sci Pollut Res Int. 2021 Sep;28(33):44587-44597.)
  13. Migration of aluminum from food contact materials to food—A health risk for consumers? Part I of III: Exposure to aluminum, release of aluminum, tolerable weekly intake (TWI), toxicological effects of aluminum, study design, and methods.. Stahl, T., Falk, S., Rohrbeck, A., Georgii, S., Herzog, C., Wiegand, A., Hotz, S., Boschek, B., Zorn, H., & Brunn, H. (2017).. (Environmental Sciences Europe, 29(1), 19.)
  14. The aluminium content of infant formulas remains too high.. Chuchu, N., Patel, B., Sebastian, B., & Exley, C. (2013).. (BMC Pediatrics, 13, 162.)
  15. Exposure to Aluminum in Drinking Water and the Risk of Developing Alzheimer’s Disease: A Bibliometric Analysis and Systematic Evaluation.. Magali, Y., Marcial, E., Yolanda, D., Mauricio, W., Gonzalo, D., Nardy, R., & Sacari Sacari, E. J. (2024).. (Water, 16(17), 2386.)
  16. Effect of an aluminum foil-processed diet on internal human aluminum burden.. Hiller, J., Göen, T., Seibold-Wulf, N., Meyer, S., & Drexler, H. (2023).. (Environment International, 177, 108000.)
  17. Bauxite mining and alumina refining: process description and occupational health risks.. Donoghue AM, Frisch N, Olney D.. (J Occup Environ Med. 2014 May;56(5 Suppl):S12-7.)
  18. Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts.. Willhite CC, Karyakina NA, Yokel RA, Yenugadhati N, Wisniewski TM, Arnold IM, Momoli F, Krewski D.. (Crit Rev Toxicol. 2014 Oct;44 Suppl 4(Suppl 4):1-80.)
  19. Accelerated lung function decline in an aluminium manufacturing industry cohort exposed to PM2.5: an application of the parametric g-formula.. Neophytou AM, Costello S, Picciotto S, Noth EM, Liu S, Lutzker L, Balmes JR, Hammond K, Cullen MR, Eisen EA.. (Occup Environ Med. 2019 Dec;76(12):888-894.)
  20. Preclinical and Epidemiological Mucoskeletal Evidence of Aluminium Toxicity: A Systematic Review.. Obani, Ifechidere & Anyachor, Chidinma & Okereke, Ifeoma. (2023).. (IPS Journal of Public Health. 3. 10-24.)
  21. Aluminum-Induced Entropy in Biological Systems: Implications for Neurological Disease.. Shaw, C. A., Seneff, S., Kette, S. D., Tomljenovic, L., Oller, J. W., & Davidson, R. M. (2014).. (Journal of Toxicology, 2014(1), 491316.)
  22. Pathophysiological mechanisms of aluminum toxicity.. Bojanić, N., Milenković, J., Stojanović, D., Milojković, M., Djindjić, N., & Gmijović, M. (2020).. (Acta Medica Medianae, 59(1), 100-109.)
  23. Aluminum exposure from parenteral nutrition in preterm infants: bone health at 15-year follow-up.. Fewtrell MS, Bishop NJ, Edmonds CJ, Isaacs EB, Lucas A.. (Pediatrics. 2009 Nov;124(5):1372-9.)
  24. Exposure to Aluminum in Drinking Water and the Risk of Developing Alzheimer’s Disease: A Bibliometric Analysis and Systematic Evaluation.. Magali, Y., Marcial, E., Yolanda, D., Mauricio, W., Gonzalo, D., Nardy, R., & Sacari Sacari, E. J. (2024).. (Water, 16(17), 2386.)
  25. Pathophysiological mechanisms of aluminum toxicity.. Bojanić, N., Milenković, J., Stojanović, D., Milojković, M., Djindjić, N., & Gmijović, M. (2020).. (Acta Medica Medianae, 59(1), 100-109.)
  26. Preclinical and Epidemiological Mucoskeletal Evidence of Aluminium Toxicity: A Systematic Review.. Obani, Ifechidere & Anyachor, Chidinma & Okereke, Ifeoma. (2023).. (IPS Journal of Public Health. 3. 10-24.)
  27. Aluminum exposure from parenteral nutrition in preterm infants: bone health at 15-year follow-up.. Fewtrell MS, Bishop NJ, Edmonds CJ, Isaacs EB, Lucas A.. (Pediatrics. 2009 Nov;124(5):1372-9.)
  28. High-Dose Aluminum Exposure Further Alerts Immune Phenotype in Aplastic Anemia Patients.. Zuo Y, Lu X, Wang X, Sooranna SR, Tao L, Chen S, Li H, Huang D, Nai G, Chen H, Pan C, Huang C, Pang Y.. (Biol Trace Elem Res. 2021 May;199(5):1743-1753.)
  29. Aluminum enhances inflammation and decreases mucosal healing in experimental colitis in mice.. Djouina, M., Deknuydt, F., Atrott, K., Esquerre, N., Altare, F., Neut, C., Arrieta, M. C., Kanneganti, T., Rogler, G., Colombel, J., Cortot, A., Desreumaux, P., & Vignal, C. (2014).. (Mucosal Immunology, 7(3), 589-601.)
  30. Aluminum vaccine adjuvants: are they safe?. Tomljenovic L, Shaw CA.. (Curr Med Chem. 2011;18(17):2630-7.)
  31. Accelerated lung function decline in an aluminium manufacturing industry cohort exposed to PM2.5: an application of the parametric g-formula.. Neophytou AM, Costello S, Picciotto S, Noth EM, Liu S, Lutzker L, Balmes JR, Hammond K, Cullen MR, Eisen EA.. (Occup Environ Med. 2019 Dec;76(12):888-894.)
  32. The impact of aluminum exposure on human health.. Bonfiglio, R., Scimeca, M. & Mauriello, A.. (Arch Toxicol 97, 2997–2998 (2023).)
  33. Toxicity and biokinetics following pulmonary exposure to aluminium (aluminum): A review.. Hadrup, N., Sørli, J. B., Jenssen, B. M., Vogel, U., & Sharma, A. K. (2024).. (Toxicology, 506, 153874.)
  34. Aluminum reproductive toxicity: a summary and interpretation of scientific reports. . Yokel, R. A. (2020).. (Critical Reviews in Toxicology, 50(7), 551–593.)
  35. The Effect of Aluminum Exposure on Maternal Health and Fetal Growth in Rats.. Badawoud MH, Abdel-Aziz G, El-Fark MM, Badawoud HM.. (Cureus. 2022 Nov 22;14(11):e31775.)
  36. A Narrative Review of Toxic Heavy Metal Content of Infant and Toddler Foods and Evaluation of United States Policy.. Bair EC.. (Front Nutr. 2022;9:919913.)
  37. The Effect of Aluminum Exposure on Maternal Health and Fetal Growth in Rats.. Badawoud MH, Abdel-Aziz G, El-Fark MM, Badawoud HM.. (Cureus. 2022 Nov 22;14(11):e31775.)
  38. Aluminum and chronic renal failure: sources, absorption, transport, and toxicity.. Wills MR, Savory J.. (Crit Rev Clin Lab Sci. 1989;27(1):59-107.)
  39. Pathophysiological mechanisms of aluminum toxicity.. Bojanić, N., Milenković, J., Stojanović, D., Milojković, M., Djindjić, N., & Gmijović, M. (2020).. (Acta Medica Medianae, 59(1), 100-109.)
  40. Pathophysiological mechanisms of aluminum toxicity.. Bojanić, N., Milenković, J., Stojanović, D., Milojković, M., Djindjić, N., & Gmijović, M. (2020).. (Acta Medica Medianae, 59(1), 100-109.)
  41. Aluminum environmental pollution: the silent killer.. Alasfar RH, Isaifan RJ.. (Environ Sci Pollut Res Int. 2021 Sep;28(33):44587-44597.)
  42. The aluminium content of infant formulas remains too high.. Chuchu, N., Patel, B., Sebastian, B., & Exley, C. (2013).. (BMC Pediatrics, 13, 162.)
  43. Aluminium content of some foods and food products in the USA, with aluminium food additives.. Saiyed, Salim & Yokel, Robert. (2005).. (Food additives and contaminants. 22. 234-44.)
  44. Aluminum bioavailability from basic sodium aluminum phosphate, an approved food additive emulsifying agent, incorporated in cheese.. Yokel, Robert & Hicks, Clair & Florence, Rebecca. (2008).. (Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 46. 2261-6.)
  45. Effect of an aluminum foil-processed diet on internal human aluminum burden.. Hiller, J., Göen, T., Seibold-Wulf, N., Meyer, S., & Drexler, H. (2023).. (Environment International, 177, 108000.)
  46. Corrosion Behavior of Aluminium-Coated Cans.. Almoiqli M, Alharbi KN, Alnuwaiser MA, Yajizi G, Alshoshan S, Baduways W, Albeladi MI, Alsanea RS, Aljohani TA.. (Materials (Basel). 2023 Jan 24;16(3):1041.)
  47. Aluminium migration into beverages: Are dented cans safe?. Veríssimo, M. I., & Gomes, M. T. S. (2008).. (Science of The Total Environment, 405(1-3), 385-388.)
  48. Deodorants and antiperspirants: New trends in their active agents and testing methods.. Teerasumran P, Velliou E, Bai S, Cai Q.. (Int J Cosmet Sci. 2023 Aug;45(4):426-443.)
  49. Real time observation of the interaction between aluminium salts and sweat under microfluidic conditions.. Sakhawoth, Y., Dupire, J., Leonforte, F. et al.. (Sci Rep 11, 6376 (2021).)
  50. Pathophysiological mechanisms of aluminum toxicity.. Bojanić, N., Milenković, J., Stojanović, D., Milojković, M., Djindjić, N., & Gmijović, M. (2020).. (Acta Medica Medianae, 59(1), 100-109.)
  51. Drinking water disparities and aluminum concentrations: Assessing socio-spatial dimensions across an urban landscape.. Weisner, M. L., Harris, M. S., Mitsova, D., & Liu, W. (2023).. (Social Sciences & Humanities Open, 8(1), 100536.)
  52. Investigation of aluminum content of imported candies and snack foods in Taiwan.. Yeh, T. S., Liu, Y., Liou, P., Li, H., & Chen, C. (2016).. (Journal of Food and Drug Analysis, 24(4), 771-779.)
  53. Safety evaluation of certain food additives and contaminants. WHO FOOD ADDITIVES SERIES: 58. (World Health Organization, Geneva, 2007. IPCS — International Programme on Chemical Safety)

Mark R. Corkins, COMMITTEE ON NUTRITION, Steven A. Abrams, George J. Fuchs, Praveen S. Goday, Tamara S. Hannon, Jae H. Kim, C. Wesley Lindsey, Ellen S. Rome;

Aluminum Effects in Infants and Children. 

Pediatrics December 2019; 144 (6): e20193148.

Read Review

Bonfiglio, R., Scimeca, M. & Mauriello, A.

The impact of aluminum exposure on human health.

Arch Toxicol 97, 2997–2998 (2023).

Read Review

Epstein SG.

Human exposure to aluminum.

Environ Geochem Health. 1990 Mar;12(1-2):65-70.

Donoghue AM, Frisch N, Olney D.

Bauxite mining and alumina refining: process description and occupational health risks.

J Occup Environ Med. 2014 May;56(5 Suppl):S12-7.

Read Review

Mark R. Corkins, COMMITTEE ON NUTRITION, Steven A. Abrams, George J. Fuchs, Praveen S. Goday, Tamara S. Hannon, Jae H. Kim, C. Wesley Lindsey, Ellen S. Rome;

Aluminum Effects in Infants and Children. 

Pediatrics December 2019; 144 (6): e20193148.

Read Review

Martin RB.

The chemistry of aluminum as related to biology and medicine.

Clin Chem. 1986 Oct;32(10):1797-806

Inan-Eroglu, E., & Ayaz, A. (2018).

Is aluminum exposure a risk factor for neurological disorders?

Journal of Research in Medical Sciences : The Official Journal of Isfahan University of Medical Sciences, 23, 51.

Read Review

Bojanić, N., Milenković, J., Stojanović, D., Milojković, M., Djindjić, N., & Gmijović, M. (2020).

Pathophysiological mechanisms of aluminum toxicity.

Acta Medica Medianae, 59(1), 100-109.

Read Review

Klotz K, Weistenhöfer W, Neff F, Hartwig A, van Thriel C, Drexler H.

The health effects of aluminum exposure.

Dtsch Arztebl Int. 2017;114:653–9

Read Review

Agency for Toxic Substances and Disease Registry

Public Health Statement for Aluminum

CAS#: 7429-90-5

Alasfar RH, Isaifan RJ.

Aluminum environmental pollution: the silent killer.

Environ Sci Pollut Res Int. 2021 Sep;28(33):44587-44597.

Read Review

Stahl, T., Falk, S., Rohrbeck, A., Georgii, S., Herzog, C., Wiegand, A., Hotz, S., Boschek, B., Zorn, H., & Brunn, H. (2017).

Migration of aluminum from food contact materials to food—A health risk for consumers? Part I of III: Exposure to aluminum, release of aluminum, tolerable weekly intake (TWI), toxicological effects of aluminum, study design, and methods.

Environmental Sciences Europe, 29(1), 19.

Chuchu, N., Patel, B., Sebastian, B., & Exley, C. (2013).

The aluminium content of infant formulas remains too high.

BMC Pediatrics, 13, 162.

Read Review

Magali, Y., Marcial, E., Yolanda, D., Mauricio, W., Gonzalo, D., Nardy, R., & Sacari Sacari, E. J. (2024).

Exposure to Aluminum in Drinking Water and the Risk of Developing Alzheimer’s Disease: A Bibliometric Analysis and Systematic Evaluation.

Water, 16(17), 2386.

Read Review

Hiller, J., Göen, T., Seibold-Wulf, N., Meyer, S., & Drexler, H. (2023).

Effect of an aluminum foil-processed diet on internal human aluminum burden.

Environment International, 177, 108000.

Read Review

Donoghue AM, Frisch N, Olney D.

Bauxite mining and alumina refining: process description and occupational health risks.

J Occup Environ Med. 2014 May;56(5 Suppl):S12-7.

Read Review

Willhite CC, Karyakina NA, Yokel RA, Yenugadhati N, Wisniewski TM, Arnold IM, Momoli F, Krewski D.

Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts.

Crit Rev Toxicol. 2014 Oct;44 Suppl 4(Suppl 4):1-80.

Read Review

Neophytou AM, Costello S, Picciotto S, Noth EM, Liu S, Lutzker L, Balmes JR, Hammond K, Cullen MR, Eisen EA.

Accelerated lung function decline in an aluminium manufacturing industry cohort exposed to PM2.5: an application of the parametric g-formula.

Occup Environ Med. 2019 Dec;76(12):888-894.

Read Review

Obani, Ifechidere & Anyachor, Chidinma & Okereke, Ifeoma. (2023).

Preclinical and Epidemiological Mucoskeletal Evidence of Aluminium Toxicity: A Systematic Review.

IPS Journal of Public Health. 3. 10-24.

Read Review

Shaw, C. A., Seneff, S., Kette, S. D., Tomljenovic, L., Oller, J. W., & Davidson, R. M. (2014).

Aluminum-Induced Entropy in Biological Systems: Implications for Neurological Disease.

Journal of Toxicology, 2014(1), 491316.

Read Review

Bojanić, N., Milenković, J., Stojanović, D., Milojković, M., Djindjić, N., & Gmijović, M. (2020).

Pathophysiological mechanisms of aluminum toxicity.

Acta Medica Medianae, 59(1), 100-109.

Read Review

Fewtrell MS, Bishop NJ, Edmonds CJ, Isaacs EB, Lucas A.

Aluminum exposure from parenteral nutrition in preterm infants: bone health at 15-year follow-up.

Pediatrics. 2009 Nov;124(5):1372-9.

Magali, Y., Marcial, E., Yolanda, D., Mauricio, W., Gonzalo, D., Nardy, R., & Sacari Sacari, E. J. (2024).

Exposure to Aluminum in Drinking Water and the Risk of Developing Alzheimer’s Disease: A Bibliometric Analysis and Systematic Evaluation.

Water, 16(17), 2386.

Read Review

Bojanić, N., Milenković, J., Stojanović, D., Milojković, M., Djindjić, N., & Gmijović, M. (2020).

Pathophysiological mechanisms of aluminum toxicity.

Acta Medica Medianae, 59(1), 100-109.

Read Review

Obani, Ifechidere & Anyachor, Chidinma & Okereke, Ifeoma. (2023).

Preclinical and Epidemiological Mucoskeletal Evidence of Aluminium Toxicity: A Systematic Review.

IPS Journal of Public Health. 3. 10-24.

Read Review

Fewtrell MS, Bishop NJ, Edmonds CJ, Isaacs EB, Lucas A.

Aluminum exposure from parenteral nutrition in preterm infants: bone health at 15-year follow-up.

Pediatrics. 2009 Nov;124(5):1372-9.

Zuo Y, Lu X, Wang X, Sooranna SR, Tao L, Chen S, Li H, Huang D, Nai G, Chen H, Pan C, Huang C, Pang Y.

High-Dose Aluminum Exposure Further Alerts Immune Phenotype in Aplastic Anemia Patients.

Biol Trace Elem Res. 2021 May;199(5):1743-1753.

Djouina, M., Deknuydt, F., Atrott, K., Esquerre, N., Altare, F., Neut, C., Arrieta, M. C., Kanneganti, T., Rogler, G., Colombel, J., Cortot, A., Desreumaux, P., & Vignal, C. (2014).

Aluminum enhances inflammation and decreases mucosal healing in experimental colitis in mice.

Mucosal Immunology, 7(3), 589-601.

Tomljenovic L, Shaw CA.

Aluminum vaccine adjuvants: are they safe?

Curr Med Chem. 2011;18(17):2630-7.

Read Review

Neophytou AM, Costello S, Picciotto S, Noth EM, Liu S, Lutzker L, Balmes JR, Hammond K, Cullen MR, Eisen EA.

Accelerated lung function decline in an aluminium manufacturing industry cohort exposed to PM2.5: an application of the parametric g-formula.

Occup Environ Med. 2019 Dec;76(12):888-894.

Read Review

Bonfiglio, R., Scimeca, M. & Mauriello, A.

The impact of aluminum exposure on human health.

Arch Toxicol 97, 2997–2998 (2023).

Read Review

Hadrup, N., Sørli, J. B., Jenssen, B. M., Vogel, U., & Sharma, A. K. (2024).

Toxicity and biokinetics following pulmonary exposure to aluminium (aluminum): A review.

Toxicology, 506, 153874.

Read Review

Yokel, R. A. (2020).

Aluminum reproductive toxicity: a summary and interpretation of scientific reports. 

Critical Reviews in Toxicology, 50(7), 551–593.

Read Review

Badawoud MH, Abdel-Aziz G, El-Fark MM, Badawoud HM.

The Effect of Aluminum Exposure on Maternal Health and Fetal Growth in Rats.

Cureus. 2022 Nov 22;14(11):e31775.

Read Review

Badawoud MH, Abdel-Aziz G, El-Fark MM, Badawoud HM.

The Effect of Aluminum Exposure on Maternal Health and Fetal Growth in Rats.

Cureus. 2022 Nov 22;14(11):e31775.

Read Review

Wills MR, Savory J.

Aluminum and chronic renal failure: sources, absorption, transport, and toxicity.

Crit Rev Clin Lab Sci. 1989;27(1):59-107.

Bojanić, N., Milenković, J., Stojanović, D., Milojković, M., Djindjić, N., & Gmijović, M. (2020).

Pathophysiological mechanisms of aluminum toxicity.

Acta Medica Medianae, 59(1), 100-109.

Read Review

Bojanić, N., Milenković, J., Stojanović, D., Milojković, M., Djindjić, N., & Gmijović, M. (2020).

Pathophysiological mechanisms of aluminum toxicity.

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