Organotin levels in seafood and its implications for health risk in high-seafood consumers Original paper

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  • Divine Aleru ID
    Divine Aleru

    User avatarDivine Aleru is an accomplished biochemist and researcher with a specialized background in environmental toxicology, focusing on the impacts of heavy metals on human health. With deep-rooted expertise in microbiome signatures analysis, Divine seamlessly blends rigorous scientific training with her passion for deciphering the intricate relationships between environmental exposures and the human microbiome. Her career is distinguished by a commitment to advancing integrative health interventions, leveraging cutting-edge microbiome research to illuminate how toxic metals shape biological systems. Driven by curiosity and innovation, Divine is dedicated to translating complex environmental findings into actionable insights that improve individual and public health outcomes.

    Read More

October 16, 2025

Researched by:

  • Divine Aleru ID
    Divine Aleru

    User avatarDivine Aleru is an accomplished biochemist and researcher with a specialized background in environmental toxicology, focusing on the impacts of heavy metals on human health. With deep-rooted expertise in microbiome signatures analysis, Divine seamlessly blends rigorous scientific training with her passion for deciphering the intricate relationships between environmental exposures and the human microbiome. Her career is distinguished by a commitment to advancing integrative health interventions, leveraging cutting-edge microbiome research to illuminate how toxic metals shape biological systems. Driven by curiosity and innovation, Divine is dedicated to translating complex environmental findings into actionable insights that improve individual and public health outcomes.

    Read More

Last Updated: 2025-10-16

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Divine Aleru

Divine Aleru is an accomplished biochemist and researcher with a specialized background in environmental toxicology, focusing on the impacts of heavy metals on human health. With deep-rooted expertise in microbiome signatures analysis, Divine seamlessly blends rigorous scientific training with her passion for deciphering the intricate relationships between environmental exposures and the human microbiome. Her career is distinguished by a commitment to advancing integrative health interventions, leveraging cutting-edge microbiome research to illuminate how toxic metals shape biological systems. Driven by curiosity and innovation, Divine is dedicated to translating complex environmental findings into actionable insights that improve individual and public health outcomes.

What was issued?

The study evaluates the presence of organotin compounds (OTCs), particularly butyltins, in seafood consumed by French populations. Organotins, including tributyltin (TBT), are biocides historically used in antifouling paints and industrial processes. The study aimed to assess the contamination levels in 159 seafood samples from four French coastal areas, including fish, mollusks, crustaceans, and canned seafood. It revealed that fish, particularly tuna, salmon, and mackerel, were the primary contributors to OTC exposure, with butyltins being the predominant compounds found. Despite the widespread contamination, the exposure levels were generally lower than the provisional tolerable weekly intake (PTWI) established by the EFSA, suggesting that the levels found in these seafood products did not pose an immediate risk to public health, though ongoing environmental control is recommended.

Who is affected?

The primary stakeholders affected by the findings of this study are high-seafood consumers, especially those living near coastal regions who consume fish and seafood products regularly. Populations in these areas may face elevated exposure to organotins, with specific groups such as older adults, women of childbearing age, and children potentially more vulnerable to the long-term health effects of OTCs. Additionally, food manufacturers, especially those producing seafood products, must ensure compliance with food safety regulations that govern heavy metal and chemical contamination. Regulatory bodies and public health agencies also play a critical role in monitoring and enforcing these safety standards to minimize public health risks from seafood consumption.

Most important findings

The study found that butyltins were the most prevalent organotins in seafood, with tributyltin (TBT) being the dominant compound in most fish samples. Fresh and frozen fish were found to have an average organotin contamination level of 5.6 μg/kg, with higher concentrations in predatory fish such as halibut and swordfish. The study revealed that fish consumption, especially of species like tuna and salmon, contributed significantly to the overall exposure to organotins. However, the levels of exposure did not exceed the provisional tolerable weekly intake (PTWI) limits set by the EFSA, indicating that the contamination, while present, was not likely to pose a major health risk. Nevertheless, regions like Le Havre and Toulon had higher levels of exposure compared to other areas, and the study emphasizes the importance of reducing environmental contamination sources to limit long-term exposure.

Key implications

For the food industry, especially seafood producers, this study underscores the need for stringent monitoring of organotin contamination in seafood products. While current exposure levels do not exceed safety thresholds, continuous monitoring and adherence to food safety regulations are necessary to prevent long-term health risks associated with chronic exposure to organotins. Public health authorities must remain vigilant in ensuring that high-seafood consumers, particularly vulnerable groups, are not exposed to harmful levels of these chemicals. Moreover, the findings suggest that reducing the environmental levels of organotins, especially in coastal and harbor areas, should remain a public health priority. The study advocates for ongoing regulatory efforts to minimize organotin levels in seafood and emphasizes the importance of reducing environmental contamination from antifouling paints and other sources.

Citation

Guérin, T., Sirot, V., Volatier, J., & Leblanc, J. (2007). Organotin levels in seafood and its implications for health risk in high-seafood consumers. Science of The Total Environment, 388(1-3), 66-77. https://doi.org/10.1016/j.scitotenv.2007.08.027

Tin (Sn)

Tin and its compounds, especially organotins, pose significant health risks ranging from neurological effects to reproductive toxicity. The HMTC program's stringent certification standards aim to minimize these risks and protect consumer health.